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    SunVax mRNA Therapeutics

    Human T cell targeted LNP kit (SV102Delivery)

    Human T cell targeted LNP kit (SV102Delivery)

    $639.00
    $639.00
    Sale Sold out
    Size

    The ready-to-use LNP kit enables specific delivery to human T cells. It is intended for research use only, supporting proof-of-concept studies and screening of mRNA constructs human PBMCs.

    Kit Components

    SV102Delivery: For Human T Cells delivery of 36 μg mRNA. The kit contains 3 x 300μL Lipid Mixture, 1 x 1.5mL Formulation Buffer, 1 x 3mg Reagent A, 1 x 400 μL Reagent B-2. For Research Use Only

    SV102Delivery Plus:  For Human T Cells delivery of 120 μg mRNA. The kit contains 5 x 600μL Lipid Mixture, 2 x 2mL Formulation Buffer, 2 x 3mg Reagent A, 2 x 600μL Reagent B-2. For Research Use Only.

    Cell-type specificity: Enabling targeted delivery to human T cells with exceptional selectivity.

    Human T cell targeted SV102Delivery™ Kits information and Supporting Data

    Table 2 The Characterizations of human T cell targeted LNP-mRNA generated by SV102Delivery™ Kits

    LNP-mRNA 

    EE (%)

    Size (nm)

    PDI

    SV102Delivery™ 

    96.5±1.7

    94.3±1.4

    0.18±0.01

    The kits exhibit excellent encapsulation efficiency, generate nanoparticles with a uniform average size of approximately 100 nm, and maintain a low polydispersity index (PDI).

    Figure 3. Stability of human T cell targeted LNP-mRNA generated by SV102Delivery™ Kits. The human T cell targeted LNP-mRNA underwent three freeze–thaw cycles prior to transfect human PBMC cells. Shown are nanoparticle size (A), polydispersity index (PDI) (B), and transfection efficiency in human PBMC cells (C).

    Figure 4. The SV102Delivery™ kit demonstrated robust transfection efficiency and cell-type specificity in human PBMC cells. In vitro transfection efficacy: Human PBMC cells were transfected with LNP–mRNA encoding eGFP, formulated using the SV102Delivery™ kit as indicated. Shown are representative FACS plots (A) and the percentage of GFP⁺ cells (B) one day post-transfection, as determined by flow cytometry.

    Store Temperature

    Formulation Mixture: -80°C

    Formulation Buffer: Room Temperature

    Reagent A: Room Temperature

    Reagent B-2: 4°C

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