SunVax mRNA Therapeutics
Instant LNP Kit (SV112 Delivery, Research Use Only)
Instant LNP Kit (SV112 Delivery, Research Use Only)
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The ready-to-use LNP kit is intended for research use only, supporting proof-of-concept studies and screening of mRNA constructs in vitro and in vivo.
Kit Components
SV112-36 Delivery for 36 μg mRNA. The kit contains 3 x 300μL Lipid Mixture, 1 x 1.5mL Formulation Buffer, 1 x 3mg Reagent A, 1 x 400 μL Reagent B-6. For Research Use Only.
SV112-120 Delivery Plus for 120 μg mRNA. The kit contains 5 x 600μL Lipid Mixture, 2 x 2mL Formulation Buffer, 2 x 3mg Reagent A, 2 x 600μL Reagent B-6. For Research Use Only and Capable in vivo.
Key features include:
- Simple and rapid use —just mix your mRNA with the formulation/lipid mixture for immediate in vitro application or concentrate for in vivo use.
- High encapsulation efficiency (EE>90%), consistent particle size (~100nm), and robust transfection performance.
- Ideal for labs and researchers lacking specialized LNP formulation expertise or equipment.
- Excellent for proof-of-concept studies, mRNA screening, and early-stage research.
These kits embody an “instant coffee”—like convenience—streamlining LNP-mRNA delivery for researchers.
For pipeline development or more complicated applications, we strongly recommend contacting us to access optimized formulations prepared by standard procedures.
Characterizations of generic LNP formulations by SV112Delivery™ and SV112Delivery™ Plus kits
Figure 1. The Characterizations of LNP SV112Delivery™ and SV112Delivery™ Plus Kits. The kits exhibit consistently high encapsulation efficiency (>90%) (A), generate nanoparticles with a uniform average size of approximately 110 nm (B), and maintain a low polydispersity index (PDI)(C).
Figure 2. Stability of LNP formulations prepared with the SV112Delivery™ kits. Formulation mixtures underwent four freeze–thaw cycles prior to complexing with eGFP mRNA in formulation buffer. Shown are encapsulation efficiency (A), nanoparticle size (B), polydispersity index (PDI) (C), and transfection efficiency in HEK 293 cells (D).
Transfection efficiency of LNP-mRNA in vitro and in vivo using SV112Delivery™ and SV112Delivery™ Plus kits
Figure 3. The SV112Delivery™ and SV112Delivery™ Plus kits demonstrated strong transfection efficacy in both in vitro and in vivo models. (A) In vitro transfection efficacy: HEK 293 cells were transfected with mRNA encoding eGFP using SV112Delivery™ kits. Shown are FACS plots of GFP (X-axis) versus Live/Dead staining (Y-axis) one day post-transfection. Data are presented as mean ± standard deviation (n=3). (B) In vivo transfection efficacy: Balb/c mice were intravenously injected with LNP-mRNA encoding Luciferase (10 µg) formulated with SV112Delivery™ Plus kits (left) or PBS (right). Shown are IVIS images at 6 hours (upper) and 24 (bottom) hours post-injection.
Store Temperature
SVD-2: Room Temperature
SVD-5: -80°C