Mouse Flt3L Fc fusion protein

Background

Flt3L is an essential growth factor that promotes the differentiation of hematopoietic cells and the development of NK cells, B cells, T cells, monocytes/macrophages and dendritic cells. Flt3L synergizes well with a number of colony stimulating factors such as G-CSF, GM-CSF, M-CSF and SCF. Flt3L is considered a stimulant of the immune system. It cooperates with IL2, 6, 7, and 15 to induce NK cell development and with IL3, 7, and 11 to induce terminal B cell maturation.

Mouse Flt3L Fc fusion protein

Source: CHO cell-derived.
Molecular Weight : 46 kDa predicted.
Purity: >90% by SDS-PAGE under reducing conditions
Activity: Effective in generating BM-derived.DC precursors (3-10 ug/ml in vitro, 10 ug per animal every 3-4 days in vivo); binds to bone marrow derived dendritic cells as shown in flow cytometry
Formulation: 0.2 um filter sterilized solution in TBS (pH 7.5)
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.