Pseudo UTP sodium solution GMP-grade (100 mM)

Description

Pseudouridine-5-triphosphate, trisodium salt solution is one of the most commonly used modified nucleoside triphosphates. It is mostly used as the reaction substrate or coenzyme of enzymes, such as in vitro transcription, RNA amplification, siRNA synthesis, etc. The modified mRNA containing pseudouridine has better nuclease stability and translation characteristics, and reduces its immunogenicity. It has a wide range of applications in the field of therapy and diagnosis.
This product is produced in accordance with GMP process requirements and provided in liquid form.

Feature

• Validated, product-specific process and analytical methods
• Product-specific stability
• Documentation follows applicable GMP guidelines
• AOF production process and raw materials (TSE & BSE) 
• Nitrosamine statement
• Regulatory support documents available
• Large-scale production
• Nucleotide in the multiple salt form（Na⁺, Tris etc) always available to meet different downstream application needs

Application

• Modified RNA synthesis and amplification
• Building block for in vitro transcription

Specification

CAS No	1175-34-4 (free acid)
Formula	C9H12N2Na3O15P3
Molecular Weight	550.10 g/moL
Purity (HPLC)	≥ 99%
Content	100 mM ± 3 mM
Structure

Component

Shipping and Storage

The product is shipped with ice packs or dry ice and can be stored at -15℃ ~ -25℃ for two years.

Documents:

Safety Data Sheet

MSDS-10650-Pseudo UTP sodium solution GMP-grade (100 mM)-HB220701.pdf

Manuals

10650_Manual_HB221110_EN.pdf