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    S-adenosylmethionine (SAM) GMP-grade (32 mM)

    S-adenosylmethionine (SAM) GMP-grade (32 mM)

    $40.00
    $40.00
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    Size

    Description

    S-Adenosyl methionine (S-Adenosyl methionine, SAM) is an auxiliary substrate involved in the methyl transfer reaction, which in the body is composed of adenosine triphosphate and methionine in the methionine adenosyltransferase under the action of synthesis. SAM is prepared in a solution of 10 mM HCl, 10% Ethanol, and pH 4 at 25℃. This product is produced by GMP process requirements and provided in liquid form.

    Features

    • Validated, product-specific processes and analytical methods
    • Product-specific stability
    • Documentation follows applicable GMP guidelines
    • AOF production process and raw materials (TSE & BSE) 
    • Nitrosamine statement
    • Regulatory support documents available
    • Large-scale production

    Applications

    • Enzymatic capping process for mRNA vaccines and therapeutics
    • Enzymatic methylations of biopolymers

    Specifications

    CAS No 485-80-3
    Formula C15H23N6O5S+
    Molecular Weight 399.44 g/moL
    Purity (HPLC) ＞ 90%
    Content 32 mM ± 2 mM
    Composition (1X) 10 mM HCl, 10% Ethanol pH 4 at 25℃
    Structure

    Components

    Components No. Name 10619ES02 10619ES25 10619ES50 10619ES76
    10619 S-adenosylmethionine (SAM) GMP-grade (32 mM) 0.5 mL 25 mL 50 mL 500 mL

    Shipping and Storage

    The product is shipped with dry ice and can be stored at -15℃ ~ -25℃ for one year.

    Figures

    • Purity Assessment

    Figure 1. The purity (HPLC) of SAM product could be over 98% (Figure 1A) and the optical purity（ee, %）of (S, S) -SAM isoform always be about 70% (Figure 1B).

    Documents:

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